"If one has not been told what to expect, the first effects of hasheesh pass by unnoticed; these consist of a certain motor and sensor excitability of the spinal cord. There is a twitching in the nape of the neck, the back and the legs, and a shivering that extends over the whole body. It is as though there were puffs of hot and cold air rising to the head; but withal there is a vague sense of comfortableness, and one finds himself in a state of great good-humor, as is the case of most persons after the absorption of a certain amount of alcohol. By degrees the excitation of the spinal cord produces effects that are more characteristic, as muscular exertion of every kind, walking, stretching, dancing, lifting heavy weights; but meantime the mind is calm. Suddenly, however, on hearing some chance remark, the patient is seized with a fit of laughing without any apparent cause, and this continues for a length of time. This having passed, he comes to himself again, and recognizes the first effects of the poison...”